Dentists May Be Able To Determine If You Have Diabetes

According to an article on diabetes and dentistry, you may not know it, but your mouth can tell doctors if your body is unhealthy. Dentists are often the first to see if you're at an elevated risk of type two diabetes, heart attack and stroke.

Dr. Ruth Cauthen of Ghent Family Dentistry helped 61-year-old Ronald Branch with his health and his job. He was struggling with controlling his blood sugar for two years, and his primary care physician was about to put him on insulin. Doctor Cauthen knew she could help.

She diagnosed him with periodontal disease, a serious bacteria infection of the mouth. Combined with his type two diabetes, it was life threatening, and could lead to a heart attack or stroke.

Dr. Cauthen pulled 14 of Ronald's teeth and got the periodontal disease under control. An infection can wreak havoc on diabetics. Once the infection was gone, Ronald's blood sugar improved.

Dr. Sheila Garris is hoping for more success stories like this. She recently attended a conference in Scottsdale, Arizona with diabetes experts and dentists. They're leading the way for dentists and doctors to work closer together helping diagnose periodontal disease and diabetes. Dr. Garris said, "Dentists may be the first people to identify diabetes by identifying periodontal disease and primary care may be the first ones to recognize periodontal disease, and they're going to need the help of the dentists to help control the diabetes."

Dr. Garris says periodental disease doesn't mean you always have diabetes but it is an indicator along with family history and obesity. If you have been diagnosed periodontal disease, you should also set up an appointment with your primary care physician to go over any other possible health problems.

Study May Set New Bar for Gestational Diabetes

According to a recent article on gestational diabetes, pregnant women with high blood sugar levels may be at risk for some of the same problems faced by women with gestational diabetes -- the risk of a Caesarean delivery and a big baby who might have health problems down the road, researchers said.

They said the seven-year international study, presented at the American Diabetes Association meeting in Chicago, may spark a new look at where to draw the line for diagnosing a woman with gestational diabetes. The condition -- in which a woman who has never had diabetes loses her ability to use insulin properly during pregnancy -- affects about 4 percent of all pregnant women. In the United States, there are about 135,000 cases of gestational diabetes each year.
Treatment usually consists of diet and exercise. If left untreated, the mother can transfer extra blood sugar to the fetus, causing the fetus' pancreas to make extra insulin to handle the overload of sugar. This extra energy can produce large babies that may have trouble breathing at birth and could become obese as a child and develop diabetes in adulthood.

The study, led by Dr. Boyd Metzger of Northwestern University's Feinberg School of Medicine in Chicago, involved 23,325 women at 15 centers in nine countries who were tracked during pregnancy. What Metzger and colleagues found is that the higher a woman's blood glucose got, the more likely the child was to be large, to be delivered by Caesarean section, to have low blood glucose needing treatment and to have high levels of insulin. "We found that some problems occurred even in ranges previously considered within the normal range for pregnant women," Metzger said in a statement.

He said it is likely that the level of a mother's blood glucose used to diagnose gestational diabetes will be lowered based on the study's findings. The study was funded by the National Institutes of Health and the American Diabetes Association.

World Waking up to Diabetes Crisis

According to an article in the UK's Telegraph, diabetes is expected to soar in developing countries over next 20 years.

There are the obvious opportunities for the insulin producers, but as diabetes can lead to blindness, heart disease, strokes and amputations, a wider group of drug makers could be involved.

Diabetes will this year kill as many people around the world as Aids, prompting scientists to call the fast-growing disease the greatest epidemic of current times.

Signs that developing countries are preparing to put some of their stretched budgets into fighting diabetes is not just good news for their people. It could create an opportunity for the drug industry. Not only will there be a large growth of diabetes sufferers in rich countries, where patients can afford the latest treatments, but the explosion of diabetes in poor countries creates an opportunity for Big Pharma to enter new markets where prices are low but volumes large.

Lars Rebien Sorensen, chief executive of Novo Nordisk, the world's largest maker of insulin, said: "Diabetes is growing fastest in Africa, Asia and Latin America. "At the same time we are seeing pressure on the US healthcare system, where there could be price controls. That is going to put pressure on global growth."

There are also opportunities to develop low-cost blood sugar monitors and even solar-powered fridges to store insulin.

The world is on the cusp of recognising the crisis and funds such as the foundation set up by former US President Bill Clinton are beginning to show an interest in creating a global fund to pay for diabetes medicines, in the same way that a fund was established for malaria, tuberculosis and Aids medicines.

One of the world's most eminent scientists working on diabetes, Paul Zimmet of Australia, told the gathering in Nairobi: "There are competing conflicts - HIV, malaria, earthquakes, Sars, climate change and water shortages. But diabetes is one of the greatest epidemics in world history."

If you have been recently diagnosed with diabetes, you may be able to get your meter and testing supplies for free. Medicare and most private insurance companies pay for these products. For more information, please visit http://www.freedomed.com.

Medical Advances Against Diabetes Haven't Benefited Women, Study Says

In a finding that partly challenges the conventional wisdom that women live longer than men, a new study suggests that the medical advances of the last few decades against diabetes haven't benefited women.

According to a recent article, researchers found that the death rates of diabetic men dropped in recent decades, while those of diabetic women increased. It's not clear why the discrepancy exists. "I do not have a clue," said Dr. Larry Deeb, President of Medicine and Science for the American Diabetes Association (ADA), when asked why women are falling behind. "But I do know that it argues that something we're doing isn't right. If you're a woman, and you have diabetes, it may be we're not aggressive enough about taking care of you."

In the new study, researchers led by Edward Gregg, an epidemiologist with the U.S. Centers for Disease Control and Prevention, examined health surveys spanning 1971 to 2000 to determine the death rates of Americans with diabetes. The researchers looked at about 27,000 people.They found that among diabetic men, the death rate from all causes dipped from 42.6 to 24.4 deaths per 1,000 persons between the two time periods. But among diabetic women, the death rate actually rose from 18.4 to 25.9 per 1,000, even as the life span of non-diabetic women grew longer.

An estimated 9.7 million American women have diabetes, and almost one-third of them don't know it. Women with diabetes are more likely to have a heart attack, and at a younger age, than women without diabetes, according to the ADA.

For more information about diabetes and related services, please visit the diabetic resource center at http://www.freedomed.com.

Rheumatoid Arthritis Drug May Help Treat Type 2 Diabetes

A recent Swiss study has found that long-term glucose levels dropped significantly after 13 weeks of treatment with a drug designed to treat juvenile rheumatoid arthritis. The study found that daily injections of Anakinra led to a drop in long-term levels of glucose in the blood, while they increased in people given a placebo. To assess whether or not this could have an effect on people with type 2 diabetes, the researchers randomly assigned 36 people to receive a once-daily placebo injection and 34 people to receive once-daily injections of 100 milligrams of anakinra for 13 weeks. The study was published in the April 12 issue of the New England Journal of Medicine.

Sometimes, beta cells -- insulin-producing cells -- in the pancreas are destroyed in type 2 diabetes as they are in type 1 diabetes. Through previous research, the study’s authors learned that a substance called interleukin-1 beta was a factor in the demise of these cells in people with type 2 diabetes. The drug Anakinra is an interleukin-1-receptor antagonist, which means it can block the action of interleukin-1 beta. "Our study is proof of concept for a mechanism underlying the disease and (may possibly) block its progression," said Dr. Marc Donath, one of the study’s authors, who added, "Interleukin-1 beta may be involved in other complications of the disease, such as arteriosclerosis. Therefore, this therapy may also prevent cardiovascular events. However, this remains to be shown."

Anakinra was well tolerated by the study participants, and Donath and his colleagues plan on conducting larger, follow-up studies of the medication. "This study points to inflammation as definitely having a role in the (diabetes) story," said Dr. Stuart Weiss, an endocrinologist at New York University Medical Center, and a clinical assistant professor of medicine at the New York University School of Medicine. But, Weiss said that while this avenue of research is "worth pursuing, I wouldn't get my hopes up for a clinical application, especially since the drug appears to lose its effectiveness over time." Additionally, Weiss pointed out that it appeared the drug was more effective in thinner people. "The authors don't really discuss this, but it's an interesting finding -- it's not what we'd expect."

For more information about diabetes and services for diabetics, please visit American Diabetes Services.

Diabetes Expert Preaches La Vida Low-Carb

In 2004, Dr. Mary C. Vernon co-authored the book Atkins Diabetes Revolution. Her specialty is working with diabetes patients and introducing them to a low-carb diet that is touted to be highly beneficial.

In December 2006 she became more widely known as she was featured in Men’s Health magazine. It was then that her efforts were brought to the forefront and she is now receiving the recognition earned for being at the forefront of the cutting edge advances being made in diabetes treatment.

According to Dr. Vernon, incorporating a low-carb diet in everyday life is the best way to keep diabetes in check. As she says, “Carbohydrate control is the best way to manage both types of diabetes -- the type with high levels of insulin secretion (usually called Type 2) and the type with no insulin secretion (usually called Type 1). In the case of high insulin secretion, low levels of dietary carbs bring the insulin levels down, which stops your body from storing fat and allows your body to begin to burn fat. This allows your body to begin to return to normal levels of blood sugar.” She has seen tremendous improvement in her patients once they make the change to the low-carb lifestyle.

Dr. Vernon further contends, “Giving [patients] control over their diabetes by giving them the tools to eat in such a way that they require less medication”.

For more information about diabetes and services for diabetics, please visit American Diabetes Services.

Tokyo Team Uncovers Possible Diabetes Cure

A Tokyo University team, led by Professor Takashi Kadowaki, might have found a link behind visceral fat-induced diabetes which might also uncover a cure for the disease. They published their findings in the U.S. medical magazine Nature Medicine.

Visceral fat (also known as internal fat) was long suspected a culprit for the onset of Type-II diabetes. When it accumulates (most often in overweight older adults), adiponectin decreases. Adiponectin is a protein hormone responsible for several metabolic processes including glucose regulation and the breakdown of fatty acid. Adiponectin works to lower blood sugar and neutral fat levels. A decline in this hormone can cause metabolic syndrome; resulting in diseases such as diabetes.

This study has revealed the inner workings of this process that were previously unclear. In tests involving mice, the researchers found two types of protein on the surface of the liver cells. Blood sugar and neutral fat levels fall when proteins and adiponectin join – which boosts fat-burning functions. Obese mice however, have visceral fat accumulated and fewer proteins on the surface of their liver cells. So when the researchers found increased proteins, the blood sugar levels would decline. The research team found that even if the quantity of adiponectin decreased in obese people, diabetes could be cured if the proteins increased.

If you or someone you know has Type-II diabetes , you may qualify for free diabetes supplies. Visit American Diabetes Services to find out.

Oral Insulin Tested to Prevent Type I Diabetes

It’s possible that oral insulin can delay or prevent Type I Diabetes. Studies are undererway now per the U.S. National Institutes of Health. More than 100 centers from the United States, Canada, Europe and Australia are included in the study. The goal from the research is to prevent the onset of type I diabetes. Researchers feel that if the disease can be delayed even by a few years it can alleviate the challenges that diabetics face of having to constantly keep their insulin in balance. The end result will be that complications arising from diabetes also will be delayed much longer.

The study tests a group of individuals most likely to develop the condition by administering an oral dose of insulin to see if it will prevent or delay its onset.

A pilot study called “The Nutritional Intervention to Prevent Type 1 Diabetes (NIP) Trial” is also being conducted on docosahexaenoic acid (DHA), an omega-3 fatty acid, to see whether it could be used to prevent the disease in infants less than five months old.

Diabetes is a disorder characterized by high blood sugar. Type I diabetes creates an autoimmune response that destroys the insulin producing cells while type 2 is a general insulin resistance. For more information about diabetes, related services and links, visit American Diabetes Services.

10-Year Old Boy Uses the Promise Ball Silent Auction to Give Back to the Medical Community – Phoenix, Arizona

It was a painful time for the Jentlies when 10-year-old Andrew was diagnosed with diabetes several months ago. Since that time, Andrew has been determined to help find a cure for the disease. Although the initial decision caused some inner conflict, he made the choice to put his cherished “mini” horse up for the silent auction at the Promise Ball in Phoenix, an annual fund-raising gala for the Juvenile Diabetes Research Foundation.

Miniature horses stand about 38 inches high and Andrew’s “mini,” named Zig Zag, was expected to start the bidding at $3,000. The only prerequisites for bidding were that the winners love him, enter him in contests and let him play in a proper field. Zig Zag is also a mini-celebrity in some circles. As a yearling, the light brown and white 4-year-old registered miniature show horse had been entered at various festivals and contests.

The Desert Southwest Chapter of the Juvenile Diabetes Research Foundation International holds the Promise Ball every winter. JDRF Desert Southwest Chapter's seventh Annual Promise Ball raises money for research to find a cure for type 1 diabetes and its complications. In 2006 , the Ball raised an astounding $2.2 million and netted $1.9 million to support research. For more information on the Juvenile Diabetes Research Foundation International, visit jdrf.org

National Diabetes Awareness Month - Last Chance to Donate

Every November, the American Diabetes Association encourages the public to learn more about Type 2 diabetes and the risks associated with the disease through National Diabetes Awareness Month. American Diabetes Services, which provides low cost or free diabetic self testing supplies to those with Medicare or qualifying insurance, supported these efforts by continuing to provide online education about this disease.

Don't Forget - Today is the last day your donations can be doubled to the American Diabetes Association. Call today at 1-800-DIABETES (800-342-2383). Your monies will go towards important diabetic research to help find a cure for Type 2 diabetes.

More Warnings on Counterfeit Diabetic Test Strips

FDA Updates its Nationwide Alert on Counterfeit Blood Glucose Test Strips

Last week, FDA issued a nationwide alert on counterfeit One Touch Basic/Profile and One Touch Ultra diabetic test strips. The Oct 23rd announcement provides two additional lot numbers of conterfeit diabetic test strips, along with descriptions of how to identify them.

The new counterfeit diabetic test strips are:

• One Touch Basic®/Profile® lot #2615211
• One Touch Ultra® lot #2691261

The following characteristics may help to identify the counterfeit diabetic test strips:

Counterfeit One Touch Basic/Profile Test Strips, lot number 2615211

• The lot number 2615211 appears on the outer carton and on the inner container (vial).
• The outer carton is written in English.
• The outer carton is labeled as 50-Count One Touch (Basic/Profile) Test Strip packages.
• A picture of a hand appears on the test strip displayed on the outer carton.
• The inner container is labeled as “plasma-calibrated”.

Counterfeit One Touch Ultra Test Strips, lot number 2691261

• The lot number 2691261 appears on the outer carton and on the inner container (vial).
• The outer carton and the inside container (vial) are written in both English and French.
• The outer carton is labeled as 50-Count One Touch Ultra Test Strip packages.
• The bottom of the outer carton does not include an NDC number.

For complete information on how to identify the counterfeit diabetic test strips, please check Lifescan's web site.

Counterfeit Diabetic Test Strips

FDA Issues Nationwide Alert on Counterfeit One Touch Basic/Profile and One Touch Ultra Blood Glucose Test Strips

LifeScan, makers of OneTouch Basic and OneTouch Ultra alerted FDA of the counterfeit diabetic test strips, which resulted in FDA in issuing a nationwide alert. The counterfeit diabetic test strips were distributed to pharmacies and stores nationwide--but primarily in Ohio, New York, Florida, Maryland and Missouri--by Medical Plastic Devices, Inc., Quebec, Canada and Champion Sales, Inc., Brooklyn, N.Y.

The counterfeit diabetic test strips can be identified by the following characteristics:

Counterfeit One Touch Basic/Profile Test Strips

• Lot Numbers 272894A, 2619932 or 2606340
• Multiple Languages- English, Greek and Portuguese text on the outer carton
• Limited to 50-Count One Touch (Basic/Profile) Test Strip packages

Counterfeit One Touch Ultra Test Strips

• Lot Number 2691191
• Multiple Languages- English and French text on the outer carton
• Limited to 50-Count One Touch Ultra Test Strip packages

Diabetics who have the counterfeit diabetic test strips should stop using them, replace them immediately and contact their physician. Consumers with questions may contact the company at 1-866-621-4855.

Transplant cures type 2 diabetic rats and without drugs

Record: Transplant cures type 2 diabetic rats — without drugs

Marc R. Hammerman, M.D. and Sharon A. Rogers have developed a 'cure' for type 2 diabetes. In a recent study, they transplant the cells of pig pancreatic primordia into a strain of rat with a disorder that closely resembles human type 2 diabetes. The cells grow into insulin producers inside the rat without triggering an attack by the rats' immune systems. This cured the rats' diabetes without the risky immune suppression drugs required to prevent rejection in other transplant-based treatments.

"The transplanted primordia not only appropriately regulated blood sugar in the type 2 diabetic rats, they also reduced insulin resistance," Hammerman said. "The rats are cured by pig insulin, which comes from the transplants and can be measured in their circulation. The rats' own insulin-producing cells in the pancreas are atrophied."

More studies need to be done to see if pig pancreatic primordia can be used to treat type 2 diabetes in humans. However if pig pancreatic primordia can prove to be comparably invisible to the human immune system and eliminate the need for need for anti-rejection drugs, they could represent a virtually unlimited source of donor organs to treat human type 2 diabetes.

Defective Diabetic Test Meters Lead to Diabetic Meter Recalls

Defective Diabetic Test Meters Lead to Diabetic Meter Recalls - American Diabetes Services

In the last two years, The Food and Drug Administration (FDA) has issued more than 20 different Class I High Risk recalls for diabetic test meters. Class I recalls are for dangerous or defective products that predictably could cause serious health problems or death.

Many of the recalled diabetic test meters could fail or provide false results, leading to possible mismanagement of diabetes. "Accuracy is the most important feature of diabetic test meters," said Lorne Yaffe, Vice President of American Diabetes Services. "Anyone who is concerned about the reliability of their meter should visit us at http://www.americandiabetes.com or call us at 1-800-933-8085 to see if they qualify for a new, free diabetic test meter delivered directly to their door."

American Diabetes Services carries the newest meters including the Ascensia Contour, FreeStyle glucose meter and the OneTouch Ultra 2. To find out if your diabetic test meters have been recalled, please visit the FDA's website at: http://www.fda.gov/diabetes/index.html

Pomegranate Juice Helps Diabetic Hearts

Pomegranate Helps Diabetic Hearts

Diabetics have increased risk for atherosclerosis, hardening of the arteries, which contributes to coronary heart disease, heart attacks, strokes, and other circulation problems. Atherosclerosis recently published a study where researchers tested the effects of pomegranate juice on atherosclerosis.

"In most juices, sugars are present in free -- and harmful -- forms," says researcher Michael Aviram, of the Technion Faculty of Medicine in Haifa, Israel, in a news release. "In pomegranate juice, however, the sugars are attached to unique antioxidants, which actually make these sugars protective against atherosclerosis."

After three months, researches found that diabetes who drank pomegranate juice had a lower risk of atherosclerosis . In addition, the pomegranate juice appeared to slow the absorption of unhealthy LDL cholesterol LDL cholesterol by immune cells.

Diabetic Foot Care Prevents Medical Complications

The Monitor - Prevention best medicine with diabetic foot care

"I was working in a bowling alley, and my leg swelled up one day," Jose O. Guerra, 57 yr old diabetic states, "I was standing up and walking too much, and I noticed my leg swelled up and got blackish from the knee down. I went to see my family doctor and he told me it had to be amputated because I got gangrene. They amputated it three inches below the left knee."

Guerra's story is one in thousands, because patients with advanced diabetes can develop several conditions and ailments as the disease progresses:

• Peripheral Arterial Disease (PAD) - (bad circulation) Diabetics can develop clogged or blocked arteries, which means blood has difficulty reaching the body's extremities. Without sufficient amounts of blood, parts of your body's tissue die, leading to infection.
• Neuropathy - (nerve damage) - Diabetics can develop a loss of sensation in their limbs, and when the foot gets damaged it might be overlooked, allowing a more serious infection to occur.

"Nine out of 10 amputations are a result of microtrauma," McAllen podiatrist Javier Cavasos said. "It comes from foot deformations and it comes from repetitive injury."

Even small problems that would not injure a non-diabetic person, such as hammertoe deformities or a long walk, could potentially harm an advanced diabetic, because they can lead to microtrauma like corns, calluses or blisters, which can break down into foot ulcers and become infected. However, diabetic preventative measures to ensure these microtraumas do not occur. Specially fitted diabetic shoes can be custom-fitted with insoles molded to a person's foot, reducing the risk of injury. Using awareness and having the issue treated in its beginning stages rather than when it's at the point that the foot has to be amputated. For more information on diabetic shoes visit American Diabetes Services.

New Diabetic Retinopathy Drug in Clinical Trials

MacuSight Announces FDA Acceptance of IND for Novel Ophthalmic Drug Candidate: Financial News - Yahoo! Finance

United States Food and Drug Administration (FDA) has accepted the MacuSight's Investigational New Drug (IND) application for its proprietary formulation of sirolimus (rapamycin). The IND covers the compound's development as a treatment for wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), a manifestation of diabetic retinopathy. MacuSight is in the process of setting up a Phase I clinical trial for diabetic retinopathy for third quarter of 2006.

We are pleased with the rapid progress of our ongoing efforts to develop our proprietary sirolimus drug candidate for the treatment of serious ocular diseases and conditions such as wet AMD and DME," said David A. Weber, Ph.D., MacuSight's president and chief executive officer. "The therapeutic potential for this product is very exciting and we are eager to initiate our Phase I clinical trials."

Sirolimus, originally known as rapamycin, has demonstrated the ability to combat ocular disease and conditions through multiple mechanisms of action including immunosuppressive, anti-angiogenic, anti- migratory, anti-proliferative, anti-fibrotic and anti-permeability activity. MacuSight believes that its sirolimus product may serve as a therapeutic solution.

Vegan Diet may be Better for Diabetics

WebWire - Vegan Diet Tops Traditional Diabetic Diet

George Washington University and the University of Toronto created a research study to compare the diabetic diet recommended by the American Diabetes Association to a traditional vegan diet, free of animal products. The goal was to examine how the diets may reduce the need for drugs in diabetes management, kidney function, cholesterol levels, and weight loss. Of the 99 diabetic participants, half were randomly put on a vegan diet and the other half on the ADA diabetic diet.

After just 22 weeks, positive improvements in both groups were observed, though the vegan diet outscored the ADA diabetic diet in every reported category. The vegan dieters lost almost 50 percent more than the ADA dieters. In addition, LDL (“bad”) cholesterol dropped by 21 percent in the vegan group, compared to just 9 percent in the ADA group.

Type 2 Diabetes Gene Ups Risks by 80 Percent

Type 2 Diabetes Gene Ups Risk by 80 Percent

Massachusetts General Hospital researcher Jose C. Florez, MD, PhD, and colleagues did genetic tests on 3,548 study participants. They looked for TCF7L2 gene variants recently linked to type 2 diabetes. They found that 1 in 10 of those with high blood sugar had two copies of the diabetes genes, and 4 in 10 had one copy. Study participants with two copies of the diabetes gene had an 81 percent increased risk of type 2 diabetes.

However, the study also showed that a person can greatly reduce that risk through diet and lifestyle change. Study participants were able to lower their risk of type 2 diabetes if they lost 5 to 7 percent of their body weight and exercised 30 minutes, five days a week.

"Even the participants at highest genetic risk benefited from healthy lifestyle changes as much as, or perhaps more than, those who did not inherit the variant," Florez said in a news release. "People at risk of diabetes, whether they're overweight, have elevated blood glucose levels, or have this particular gene variant, can benefit greatly by implementing a healthy lifestyle."

Additional diabetic resources:

• Diabetes and Exercise - American Diabetes Services
• Getting Started - Exercise - American Diabetes Association
• Do you qualify for Free Diabetic Testing Supplies from FreedoMed

Diabetic Research Funded by Shopping Website

Diabetic Girl Hopes to Fund Cure Through Her Website: Shop2Cure.com

Allie Beatty, the founder and developer of Shop2Cure.com, has been a type I diabetic for over 20 years. She as created Shop2Cure.com to raise monies to fund these organizations doing diabetic related research:

• American Diabetes Association - mission is to prevent and cure diabetes, and to improve the lives of all people affected by diabetes. The American Diabetes Association funds research, publishes scientific findings, provides information and other services to people with diabetes, their families, health care professionals and the public and advocates for scientific research and for the rights of people with diabetes.
• Join Lee Now - is the fundraising arm of The Iacocca Foundation. It was developed in response to the discovery made in 2003, when researchers that The Iacocca Foundation had supported for several years made history by reversing and curing type 1 diabetes in mice. The next step is to translate this research to humans, with a price tag of $11.5 million. Join Lee Now has raised over $10 million and the launch of Phase I of clinical trials is $1.5 million shy of potentially curing type I diabetes

Using Shop2Cure.com is as simple as clicking through banner ads that provide coupons, promotions, free shipping or information to hot selling products to shop their affiliates. Shop2Cure.com earns advertising revenues based on the total dollar amount of the purchase. Eighty percent of Shop2Cure.com earnings are donated to nonprofit organizations.